Prospects for molecular epidemiology of leprosy

Prospects for epigenetic epidemiology.

Epigenetic modification can mediate environmental influences on gene expression and can modulate the disease risk associated with genetic variation. Epigenetic analysis therefore holds substantial promise for identifying mechanisms through which genetic and environmental factors jointly contribute to disease risk. The spatial and temporal variance in epigenetic profile is of particular relevanc...

Recent advances in the molecular epidemiology of leprosy.

Recent advances in the molecular epidemiology of leprosy through genotyping of variable number tandem repeats (VNTRs) and single nucleotide polymorphisms (SNPs) are described. VNTRs with a broad range of diversity are useful genotyping tools for analyzing transmission in community areas, and SNPs and VNTRs with a small degree of variation are favorable for investigating the global transmission ...

Molecular epidemiology of leprosy based on VNTR typing in Thailand.

Recently about 500 new cases of leprosy have been reported each year in Thailand. In addition to a steady rate of new case detection, Thailand is in Southeast Asia where leprosy is endemic in neighbouring countries; therefore, strain differentiation could be useful in tracing origins and routes of infection, and general leprosy surveillance. To identify suitable markers for differentiation of M...

Epidemiology of Leprosy

Epidemiology of Leprosy

gnii ln the Bombay Presidency in general, and in the Kolaba district (where I am working) in particular, I have observed that the incidence of leprosy amongst Mohammedans is very low as compared with Hindus (of the same social status), although the habits and the conditions under which both these communities live are more or less identical. I believe this fact might have been noticed by other o...